[A trial of using sulperazone (cefoperazone/sulbactam) in the combined treatment of patients with a burn infection]. / Opyt primeneniia sul'perazona (tsefoperazon/sul'baktam) v kompleksnom lechenii bol'nykh s ozhogovoi infektsiei.

The experience with the use of sulperazone (a combination of cefoperazone, a 3rd generation cephalosporin, and sulbactam, a beta-lactamase inhibitor, Pfizer, USA) in the treatment of 25 patients with burns and deep burns (1 to 85 and 1 to 70 per cent of the body surface affection respectively) is described. The drug showed high clinical efficacy in the treatment of the infected burn wounds and infectious complications of the burns. Excellent and good results of the treatment were stated in 84 per cent of the patients. The extended affections and wound dissemination by multicomponent associations of polyresistant microbial strains lowered the microbiological efficacy of the treatment which amounted to 58 per cent. Rapid development of resistance to the drug in staphylococci was noted. The tolerance of sulperazone was good. The side effects were observed only in 1 patient.

[Deep electrothermal burns]. / Elektrotermicheskie glubokie ozhogi.

Five-year experience in the treatment of patients with severe electrotrauma are analysed. They accounted for 3.1% of the total number of patients with burns. The treatment of such patients in of a long duration and expensive. This trauma nonetheless leads to irreversible affection of the organism and disability. The main success is determined by early surgical treatment before the development of pyo-inflammatory processes in the injured tissues.

[Clinico-morphological changes in a burn wound after electric stimulation with pulsatile current]. / Dinamika kliniko-morfologicheskikh izmenenii v ozhogovoi rane pri élektrostimuliatsii impul'snym tokom.

The healing of sluggishly postburn wounds after local electrostimulation (ES) with the use of current-conducting carbon tissue as the electrode was studied in 12 patients. Analysis of the clinical data which were corroborated by the results of morphological and biochemical studies confirmed the marked stimulating effect of local ES which facilitates successful taking of dermal autografts and healing of burn wounds. The obtained data are evidence that the method of ES through a current-conducting carbon tissue is promising in the complex of measures for local treatment of burn wounds.

[Treatment of patients with thermal lesions with ointments on water-soluble base]. / Lechenie bol'nykh s termicheskimi porazheniiami maziami na vodorastvoromoi osnove.

Treatment of patients with thermal burns by ointments prepared on a water-soluble base (Dioxidine and Dioxicol) makes it possible to reduce the bacterial dissemination within a short time and prepare the wound for autodermoplasty which, in turn, reduces the danger of the development of infectious complications. In addition to a marked antimicrobial effect, the ointment possess high hydrophobic and hydrophilic properties and do not induce allergic reactions and side effects.

[Correction of immunologic disorders in patients with burns]. / Korrektsiia immunnykh narushenii u bol'nykh ozhogovoi bolezn'iu.

Addition of immunomodulating therapy with Thymalin, a thymus agent, to the multimodality therapy of burnt patients contributes to a rapid normalization of immunological parameters. The most marked immune response was observed 7-10 days after a therapy course initiated in the early periods of burn disease in patients with severely depressed T-system immunity and a high sensitivity to the drug. Inclusion of a donor blood leukomass transfusion course activates the cellular link of the immune system just after the treatment course, but fails to favour a stable normalization of thymus-dependent lymphocyte ratios.